Mike it could take one drawing or a thousand drawings. No body can answer that question. i've seen drawings where there were 9 nines in 15 drawings and some other duplicate numbers so you would think the quad 9's were hot and all 2's hit. When quads come there are very few signs not to say there aren't any signs but. When a bunch of tripple or double digits start hitting within days of each other then somtimes the quads hit. Many times quads hit with no warning what so ever. Pick 4 numbers don't reveil themselves ahead of time you have to seek them out. And mostly getting the right ones will come from experance. With being able to understand the history of the numbers drawn and they way they were being drawn. And follow simple rules. like if 63XX comes out that is a pair then a couple days later 36xx comes out then a week later 63 comes again with some other number and there pairs start working and you start working with those pairs.
look at other states number history to get examples of how this works.