I've actually tried playing 100 quick picks for fantasy 5 whenever the jackpot was over $200k around the time Fantasy 5 2nd Chance draw was in its debut. I've tried about 10 times and I did not use any wheeling system (its for those who are supersititious that a number will not repeat or a number is hot, when in reality its all independant events).
I got about 8 to 15 Free Plays for 2 out of 5 matches (1 in 10 odds)
I got about 1 to 3 ~$15-19 prizes for 3 out of 5 matches (1 in 103 odds)
I lucked out with a 4 out of 5 match (1 in 3389 odds) for a pari-mutuel amount of $550, otherwise my ROI would have been more disasterous
Out of all the 20 entries (5 plays earns an entry) I punched in on those 10 times. I did not win any of the drawings.
After your first game of $100, your next 100 QP play might cost about $70 - 80 depending on your outcome.
It is the best draw game that the CALottery in my opinion. It is only that I like the fact there is a guaranteed winner for the 2nd chance scratcher draw where as Fantasy 5 can roll over with no winner.