What's the best shot here?
IL lotto 6 of 6, odds against 1 in 20,358,520
MM with the Megaplier, 5 + 0 pays $1,000,000 5 0 1 in 3,904,701
PB PB 5 numbers; no PB $1,000,000 $2,000,000 1 in 5,153,632.65
Those who run the lotteries love it when players look for consistency in something that's designed not to have any. So many systems, so many theories, so few jackpot winners.

There is one and only one 'proven' system, and that is to book the action. No matter the game, let the players pick their own losers.