A Florida man was arrested late Thursday after a road rage confrontation in Tampa turned deadly.

Teddy Smith, 44, allegedly became enraged when Gilbert Serna, who was a passenger in a truck, apparently spit on his BMW Wednesday morning.

Serna, 56, had a habit of spitting out of the window, his sister told ABC station WFTS.

But when the truck and Smith's BMW were stopped on Fowler Avenue about 11 a.m., the spitting led to an argument.

That's when Smith allegedly stabbed Serna in the upper body, according to the police report.

 The police performed CPR on Serna but he died from his injuries at the hospital.

Smith, meanwhile, fled, police said. The driver of the truck gave chase, but he eventually stopped at the corner of W 109th Avenue and N Ashley Street.

Sometime afterward, Smith went to the District Two substation to talk to police. He told them that “he shouldn’t have spit on.”

At that time, Smith wasn’t arrested and was told that he could leave at any time.

But late Wednesday, the police located the BMW and on Thursday they arrested Smith after a short foot chase, Tampa police said.

He was charged with second-degree murder, police said.