Scam Alert:

When considering any at-home job, put up the scam-detection radar.

Watch for these positive indicators of "real" employment:

The hirer is an established company.
The ad includes the company name and does not have applicants reply to a blind e-mail address.
Human resources personnel are available for questions.
There is mention of information commonly associated with "real" employment (benefits, vacations, policies, etc.).
There is an application and interview process, not simply an e-mailed offer.
The employer can detail the job duties and expectations.
References/work samples are requested