The best way to stop SPAMers is to block the Domain Name. Most of the time, when you don't know who sent you the e-mail, if the Domain Name is not something you would associate with a well known website, like aol.com, yahoo.com, lotterypost.com, or something like that...  sometimes it better to just block the entire (site) Domain Name.  I.E. my e-mail is 'jadelottery@aol.com' the Domain Name is 'aol.com'. Block the 'aol.com' part and anyone sending from that Domain Name can not send you e-mail.

Just a thought.